Etiology of suspected pneumonia in adults admitted to a high-dependency unit in Blantyre, Malawi.
نویسندگان
چکیده
The microbiologic etiology of severe pneumonia in hospitalized patients is rarely known in sub-Saharan Africa. Through a comprehensive diagnostic work-up, we aimed to identify the causative agent in severely ill patients with a clinical picture of pneumonia admitted to a high-dependency unit. A final diagnosis was made and categorized as confirmed or probable by using predefined criteria. Fifty-one patients were recruited (45% females), with a mean age of 35 years (range = 17-88 years), of whom 11(22%) died. Forty-eight (94%) of the patients were seropositive for human immunodeficiency virus; 14 (29%) of these patients were receiving antiretroviral treatment. Final diagnoses were bacterial pneumonia (29%), Pneumocystis jirovecii pneumonia (27%), pulmonary tuberculosis (22%), and pulmonary Kaposi's sarcoma (16%); 39 (77%) of these cases were confirmed cases. Fifteen (29%) patients had multiple isolates. At least 3 of 11 viral-positive polymerase chain reaction (PCR) results of bronchoalveolar lavage fluid were attributed clinical relevance. No atypical bacterial organisms were found.
منابع مشابه
Methicillin Resistant Staphylococcus Aureus in Ventilator Associated Pneumonia in Toxicological Intensive Care Unit
Background: Methicillin resistant Staphylococus Aureus (MRSA) is a cause of nosocomial infections at intensive care unit (ICU), which imposes a high mortality and morbidity on the health care systems. The objective of this study was to evaluate the role of MRSA in patients with clinically suspected ventilator associated pneumonia (VAP) in toxicological ICU admitted patients.Methods: This ...
متن کاملIncidence, risk factors and prognosis of nosocomial pneumonia in adult patients admitted in the intensive care unit
Introduction: Hospital acquired pneumonia (HAP) is the second most commonly reported hospital infection and the most common infection in the intensive care unit (ICU). Identification of risk factors and determinants of prognosis in the occurrence of HAP and ways of prevention can be effective in reducing the incidence and mortality of these infections. In this way, we investigated, the incidenc...
متن کاملPoint-of-care lactate and creatinine analysis for sick obstetric patients at Queen Elizabeth Central Hospital in Blantyre, Malawi: A feasibility study.
BACKGROUND To achieve good outcomes in critically ill obstetric patients, it is necessary to identify organ dysfunction rapidly so that life-saving interventions can be appropriately commenced. However, timely access to clinical chemistry results is problematic, even in referral institutions, in the sub-Saharan African region. Reliable point-of-care tests licensed for clinical use are now avail...
متن کامل837Early Goal Directed Therapy for Acute Bacterial Meningitis in Malawian Adults
Malawian Adults Emma Wall, MBChB, MRCP, DTM&H, MRes; Khumbo Kasambala; Veronica Mlozowa; Malango Msukwa MA; Mavuto Mukaka, PhD; Theresa Allain, FRCP PhD; Mulinda Nyirenda, MMed; Brian Faragher, PhD; Robert Heyderman, PhD; David Lalloo, MB, BS, MD; Malawi-Liverpool-Wellcome Trust Clinical Research Programme, Blantyre, Malawi; Liverpool School of Tropical Medicine, Liverpool, United Kingdom; Depa...
متن کاملPredictors of Utilisation of Skilled Maternal Healthcare in Lilongwe District, Malawi
Background Despite numerous efforts to improve maternal and child health in Malawi, maternal and newborn mortality rates remain very high, with the country having one of the highest maternal mortality ratios globally. The aim of this study was to identify which individual factors best predict utilisation of skilled maternal healthcare in a sample of women residing in Lilongwe district of ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- The American journal of tropical medicine and hygiene
دوره 85 1 شماره
صفحات -
تاریخ انتشار 2011